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Sustained-release niacin to support cardiovascular health
Niacin-SR supplies 500 mg of niacin (also known as nicotinic acid or vitamin B3), an essential B vitamin, in a sustained-release matrix that allows the niacin to be slowly released over a period of several hours. Niacin is a water-soluble nutrient, also known as vitamin B3 or nicotinic acid. Niacin-SR is provided in a scored tablet, which allows for easier adjustment of intake if needed.
Key Benefits and Features:
|
Serving Size: 1 Vegetarian Tablet |
Amount/Serving |
| Niacin (as niacin) | 500 mg |
Other Ingredients: Vegetarian stearine, cellulose, silicon dioxide, magnesium stearate, and croscarmellose sodium.
Does Not Contain: Milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, sesame, synthetic colors, flavors, or preservatives.
Non-GMO, Vegetarian
Adults: 1 tablet daily with food, or as directed by a healthcare professional.
Warning: Consult with your physician if you are pregnant or nursing, have any medical condition, are taking prescription drugs, or are under the age of 18 years. Some forms of niacin may cause temporary flushing, tingling, itching, rash, or stomach upset.
Consult your physician about periodic liver function testing if using this product long-term, or if you are taking more than 500 mg daily. KEEP OUT OF REACH OF CHILDREN.
Storage: Store at room temperature (59°F-85°F).
How does Niacin-SR support normal cholesterol metabolism?
Niacin is readily absorbed in the stomach and small intestine where it is transported first to the liver and then to various tissues throughout the body. It is thought that niacin reduces the entry of free fatty acids into the liver thereby reducing the rate of very low-density lipoprotein (VLDL) cholesterol production. A decline in the liver’s production of VLDL reduces the circulating levels of VLDL available for conversion to LDL cholesterol.
Why is Niacin-SR provided in a sustained-release form?
Niacin-SR allows the niacin to be released to the body at a slow rate rather than delivering the entire amount at once. Slow release helps maintain serum levels of niacin for a longer period of time. In addition, while high amounts of immediate-release forms of niacin often cause a reaction known as a "niacin flush" experienced as a temporary itching, tingling, or warming of the skin, Niacin-SR’s sustained-release formulation helps minimize this reaction and improves compliance. The nicotinic acid form of niacin, as used in Niacin-SR, is the most effective form for supporting normal cholesterol and lipid metabolism. Other forms of niacin such as nicotinamide (also known as niacinamide) and inositol hexaniacinate contain little or no free nicotinic acid and have not demonstrated comparable efficacy.
Are there any side effects?
As mentioned before, a possible side effect of niacin supplementation is a "niacin flush." While Niacin-SR’s sustained-release matrix helps to minimize this reaction, some individuals may still be sensitive even to the slow delivery system. This potential side effect is caused by a vasodilatation of cutaneous blood vessels which may produce a temporary tingling and warming sensation on the face, neck, arms, and chest. While the flushing sensation is not desirable, it is completely safe. This side effect usually disappears with continued use and may be reduced or eliminated when high doses of niacin are taken with a baby aspirin.
Use of high daily amounts of niacin, particularly in delayed-release forms, may also produce a temporary elevation in liver enzymes. Make sure your healthcare professional monitors your liver enzymes while taking this product and makes adjustments to your daily intake of niacin as he or she sees prudent.
